Skip to content

The Future of SIBO Treatment

Small intestinal overgrowth of bacterial (SIBO) treatment can include antibioticsthat decrease the amount of bacterial growth and calcium, vitamin, and magnesium supplements that aid in addressing nutritional deficiencies. Certain diets, like the elemental diet or the low-FODMAP diet can also be employed to help sufferers avoid food triggers that can cause symptoms.

This article will explain the various choices you and your health doctor may discuss in treating SIBO which includes taking antibiotics as well as changing your diet.

Antibiotic Therapy

The “gold most effective” method of treating SIBO is to use antibiotics to limit the growth of bacterial in the small intestinal tract. The medications are also believed to reduce inflammation of the lining of the small intestinal tract that can lead to malabsorption.

SIBO is classified by two methods:

Methane-dominant SIBO typically causes constipation.
Hydrogen-dominant SIBO causes diarrhea.

Antibiotics are prescribed to treat both kinds of SIBO. However, in addition to antibiotics methane-dominant SIBO might require taking fiber.

There aren’t specific SIBO treatment guidelines and further research into using antibiotics in treating SIBO is required. There are a variety of types of antibiotics employed to treat SIBO and other bacterial infections, but which one is most appropriate for a particular person and in what dose is not yet fully known.

Xifaxan Initial Treatment

At present, the main treatment for SIBO is Xifaxan, as the majority of patients appear to be benefited from it. Studies have shown that Xifaxan is one of the brand names to refer to the generic drug called rifaximin eliminates different strains of bacteria and improves symptoms.

Within the human body, Xifaxan does not enter the bloodstream. This decreases the chance of adverse negative effects and increases the ability of the drug to work directly against the bacteria present in the small intestinal.

Another advantage is that Xifaxan has a minimal impact on bacteria within the large intestine. This decreases the risk of symptoms of the gastrointestinal tract and yeast infections that are often seen when using other antibiotics.

For more information on SIBO treatment visit

While certain side reactions are possible however, generally speaking, Xifaxan is considered a drug that is safe.

Despite the promising researchfindings, Xifaxan hasn’t been recognized by the FDA to treat SIBO (although it has been approved to treat diarrhea-related IBS and travelers diarrhea). So prescribing Xifaxan to treat SIBO is thought of as “off-label” usage.

In the absence of research, there’s no consensus on the appropriate dosage and duration to use Xifaxan to treat SIBO. In clinical studies high doses will be effective over doses with lower efficacy. In the clinic, Xifaxan typically prescribed in doses of 2 weeks. Other antibiotics are sometimes administered concurrently or with repeat courses when needed.

Dietary Interventions

In addition to taking antibiotics to control intestinal bacteria, you could be able to control SIBO symptoms by taking care of the nutritional deficiencies of your diet or avoiding foods that trigger symptoms.

Nutritional Deficiencies

If you have been diagnosed with SIBO You should consult with your physician to determine and correct any nutritional deficiencies you may have. Supplements should be considered to treat any or all the following minerals and vitamins in the event of a deficiency:

Vitamin A
Vitamin B12
Vitamin D
Vitamin E

If your physician thinks that steatorrhea, or another form of fat malabsorption may be present, they might suggest that you take the pancreatic enzyme supplement.

Elemental Diet

The elemental diet is that is restricted to liquids that are medically designed. The nutrients consume in the most basic form, making it easy to take in and digest the nutrients.

A few health experts advocate a basic diet with antibiotics for those suffering from SIBO due to the fact that it limits what food items that bacteria could be able to attack. Additionally, it may reduce the amount of general gut bacteria which can help alleviate symptoms.

It is essential to conduct more research to better understand the advantages of this difficult-to-follow diet plan. In the meantime, it is suggested to not attempt this at home using homemade formulas due to the possibility of nutritional deficiencies.

The Low-FODMAP Diet

Diets that are low in FODMAPs were developed to alleviate IBS symptoms. IBS. The goal is to limit the intake of carbohydrates or those with high FODMAPs, which can cause IBS symptoms.

In SIBO it is possible that one of five FODMAP types, lactose and fructose are ineffectively absorbed because of inflammation in the intestinal lining. Alongside these two, other unabsorbed FODMAPs might be fermented by bacteria that are not properly residing within the small intestinal tract, which can lead to gastric and other digestive problems.

Thus, a low-FODMAP diet might be helpful in treating SIBO as eating fewer carbohydrates can “starve” these bacteria that live in the small intestinal tract. As of now there are no clinical studies on this topic.

Before You Change Your DIet

It is best to stick to an FODMAP diet with the help of an accredited nutritionist or dietician.

It is not clear the benefits of a low-FODMAP diet in a person who is taking antibiotics to treat SIBO. Certain experts believe that it could hinder the effectiveness of antibiotic treatment since it puts bacteria inactive. Instead, it is suggested that you consume a healthy diet when you are taking antibiotics. Following the course of antibiotics it is possible to adhere to the low-FODMAP diet in order to avoid future SIBO instances.

To address the root causes

Before giving antibiotics the doctor will conduct an extensive physical examination along with a detailed medical examination to determine whether your SIBO symptoms may be related to an underlying illness.

Conditions that affect the Small Intestines

Certain illnesses can trigger the development of SIBO and could cause a decrease in digestive function in the stomach and the small intestine. They include:

Gastroparesis, which impacts the stomach’s nerves can cause a slowdown in digestion. It is often linked to diabetes and, in the event that blood sugar levels are stabilized, it could disappear.
Celiac disease, an auto-immune illness that affects your small intestine, results in problems with absorption within the digestive tract. Celiac patients are more at risk of developing SIBO. In these cases adhering to an elimination of gluten is crucial to reduce symptoms and improve general health.

Drug-related Side Effects

Sometimes, a medication taken to treat a health issue can cause conditions that can cause SIBO. The medications that cause SIBO include:

Opiate drugs are usually prescribed for the relief of pain
Proton Pump Inhibitors (PPIs) are typically prescribed to treat GERD

The discontinuation of these medications could aid in reducing SIBO symptoms.

Future of SIBO Treatment

When more study is conducted on SIBO there are more treatment options likely to develop. One particularly exciting area of research is the creation of new technology that can precisely determine the kind and amount of bacteria that are present in the small intestine of a person. While this is happening, other possibilities are being considered as safe, effective treatment options for SIBO.
Herbal Formulations

In a study published in a study, the herbal formula was shown to be at the very least efficient as Xifaxan in treating SIBO.

Herbal formulas can also help prevent the negative side negative effects of antibiotics and can treat patients for whom antibiotics aren’t working. They can also help prevent the return of SIBO.

Prokinetic Medicines

Prokinetic drugs are prescribed to treat gastrointestinal issues as well as acid reflux. They can also aid in the treatment of SIBO. Research suggests that these drugs could be particularly beneficial for people suffering from SIBO as well as scleroderma. These medication can be helpful as they could boost the capacity in the intestinal small-intestine’s “cleansing Wave” to flush out bacteria.


Probiotic supplements can be beneficial for treatment of SIBO since they’ve been shown to have an effect on the makeup of bacterial, enhance the gut lining’s health as well as to decrease inflammation. There is however no research into the efficacy of probiotics for treating SIBO.

Prevention of Relapse

Despite the success of treating SIBO through medications, relapses are not uncommon. There isn’t much information on the best approach to stop SIBO symptoms from recurring. The most effective procedure is to prescribe an antibiotic course instead of requiring people to alter their diet. If needed, another course of antibiotics is recommended.

It isn’t easy to know what changes to your diet will be like. It could be helpful to stick to the low-FODMAP dietary guidelines for a short period of time. It could also be beneficial to stay clear of foods that contain artificial sweeteners like saccharin, aspartame and sorbitol. They have the potential to interact with bacteria in the small intestinal tract.


SIBO is extremely uncomfortable and can can affect the quality of your life, but it doesn’t need to be this way. The majority of antibiotics are efficient in treating SIBO. However, it can require multiple antibiotics or you might require repeat treatments in the event that SIBO is recurring.

In addition to taking medications It is recommended to alter your diet so that you’re getting the right nutrients as well as to avoid inflammation.

SIBO is often caused by digestive disorders that can affect. The treatment of these diseases and conditions can decrease levels of microbes present in the intestines. It can also reduce inflammation.

Researchers continue to search for ways to alleviate SIBO symptoms. The aim is to lessen negative effects as well as reduce the chance of SIBO getting worse after antibiotics clear the bacteria.